Experience Matters

With over 25 years in practice, Dr. Joni Collins, DMS, PA-C, CAC, brings the perfect blend of clinical expertise, innovation, and artistry to precision aesthetic and regenerative medicine. She is dedicated to advancing the medical field while delivering highly personalized care to each of her patients. Joni is mother, an inventor, and a patent holder who has taught and trained over 1200 professionals nationwide. She currently mentors over 350 PAC and NP mentees. Since 2020, over 40 medical practices utilize her patent pending and award winning protocol.

Her mission is simple: to help you age with confidence, vitality, and intention because true optimization is about more than aging well. It is about truly living.

We Engineer Human Biology & Aesthetic Outcomes

A simple systems-based approach to help support cellular health, aesthetic balance, and long-term cellular optimization.

Personalized, protocol-driven care designed to restore, optimize, and enhance your body from the inside out.

01

Cellular Optimization

We begin by supporting the body at the cellular level for better overall function.

02

Internal Regulation

We focus on inflammation, hormones, and microvascular health to support internal balance.

03

Structural Aesthetic Engineering

We approach aesthetics with precision, structure, and natural-looking outcomes.

04

Maintenance & Longevity

We help you maintain your results while supporting long-term vitality.

THE 1228 DIFFERENCE

Ready to Begin?

Book your consultation and start your personalized journey to optimized health and natural results.

‍ ‍

NOT SURE WHERE T0 BEGIN?

Begin with a Consultation Designed to Optimize How You Age

An Aesthetic or Precision Medicine Consultation is often the most valuable first step in creating meaningful, lasting results.

At our practice, we believe aging well is about more than looking refreshed, it is about truly living with confidence, vitality, and intention. During your consultation with Dr. Joni Collins, DMS, PA-C, CAC, we’ll discuss your goals, review your top three wishlist services, and develop a customized treatment plan designed specifically for you.

Whether your focus is aesthetics, wellness, prevention, or overall optimization, your consultation is the foundation for a personalized plan that supports how you want to look, feel, and live.

THE CONSULTATION:

AN OPPORTUNITY TO CREATE A LONG TERM GAME PLAN

PRECISION

Aesthetic and Regenerative Medicine

Precision Aesthetic & Regenerative Medicine is a personalized approach to aging well that blends advanced aesthetics, health optimization, and regenerative therapies to help you look, feel, and live better.

At Twelve Twenty Eight Wellness, we believe true beauty and vitality begin at the cellular level.

Our work is rooted in the art and science of personalized, precision-based regenerative medicine, using the body’s own innate intelligence to support repair, resilience, and long-term wellness. We do not see aesthetics as separate from health. We see the skin, body, mind, and spirit as deeply connected systems that deserve to be understood, supported, and optimized together.

Through advanced regenerative aesthetics, cellular therapies, and whole-person wellness strategies, our goal is to help restore balance from within. By listening closely to your story, studying your unique biology, and creating a plan designed specifically for you, we support healthier cellular function, improved vitality, and a more radiant expression of well-being.

This is not about chasing a trend or masking the surface. It is about honoring your body’s capacity to heal, renew, and thrive.

We invite you to experience a more intentional approach to health, beauty, and longevity. One that is deeply personal, medically guided, and designed to help you feel as vibrant as you look.

Your next chapter of optimization begins here.

The 1228 Biohack TM

A proprietary regenerative cellular optimization protocol that integrates epigenetic testing, microvascular health testing, and advanced peptide therapies to optimize cellular function, metabolism, for high performing individuals.

The Annual 1228 Regenerative Precision Membership

12 months of personalized cellular optimization customized based on your epigenetic history, your past medical history, and your lifestyle. Initial testing includes epigenetic- genomic testing, microvascular analysis, and hormone evaluation. Offerings include regenerative therapies- Peptides, PRF, Bioharmonic Optimization, Skin Analysis, Cryotherapy and more… Quarterly labs and monthly one on one follow ups with our Board Certified Provider.

Personalized Cellular Therapy

Customized cellular therapies: allogenic (Creska), autologous ( harvest your own cells and send for replication and deployment. L2Bio partnership). We age every day. It is imperative to have ongoing treatment strategies.

Introducing The Twelve Twenty Protocol™

To bring all of this together, we created The Twelve Twenty Protocol™.

This is our signature framework and our high-touch, medically guided roadmap for skin and whole-body optimization.

The Twelve Twenty Protocol™ is not a single treatment, a single product, or a magic wand. It is a personalized process of assessment, preparation, treatment, and reassessment. It may include epigenetic testing, microvascular health analysis, advanced regenerative therapies, medical-grade skincare, and precision wellness strategies designed around your unique biology. This protocol allows us to meet your skin and body exactly where they are. Not where a trend says they should be. Not where a generic treatment plan assumes they are. Exactly where they are. Your care should be as individual as your DNA.

That is the promise behind The Twelve Twenty Protocol™.

Our science-based skin care system develops a personalized skin care routine based on your unique Baumann Skin Type®.

Get your personalized skincare regimen recommendation by taking the STS Skin Type Quiz. Or shop now from a selection of the best dermatologist recommended skincare brands.

For Medical Professionals

Advanced training in regenerative aesthetic medicine, protocols, and business growth.

Other Locations
Florida

We also serve the state of Florida via our vintage Mobile Cellular optimization Airstream specializing in Internal Medicine. #cellular optimizationiswhereweparkit

QUESTIONS?

‍ ‍770.250.4447

We are Located in Roswell

138 Marietta Hwy
Roswell, Georgia 30075

We are located in historic Roswell, Georgia. Just around the corner from the Avenues of East Cobb and are conveniently located less than 1/4 of a mile from the Mill at Roswell and walking distance to Canton Street. We absolutely love our #littlehouseonthehill where we offer an extensive Aesthetic and Regenerative Precision Medicine.